Medical and Mental Health Complications
of Lafora Disease: A Case Report Glen
A. Palmer, Ph.D., ABPN & Forrest H. Mark, M.S., L.P.C., BCBA

Lafora disease is a rare neurometabolic condition caused by a mutation in the EPM2A and/or EPM2B genes. The disorder is neurologically progressive, and the disease is eventually fatal. A form of progressive myoclonic epilepsy, it can produce a variety of complications including intellectual disability, various seizure disorders, mental health difficulties, and dementia. The authors describe the symptoms of Lafora disease; a case study of a young male who was diagnosed with the disorder is presented. The etiology of Lafora disease and progression of the disorder are described. Implications for treatment of the disorder and palliative care are briefly discussed.